Dr. Someswara Rao Sanapala

Assistant Professor

Areas of Interest : Carbohydrate Chemistry & Oligosaccharide synthesis

• Synthetic Organic Chemistry
• Glycoconjugate Vaccines
• Vaccine Adjuvants
• Conjugation methods
• Regio and Stereoselective Construction of Glycans

Education

• Ph.D, Indian Institute of Technology Bombay, India (2016)
• M.Sc, (2008)
• B.Sc, (2006)

Professional Experience

• Assistant Professor (2022 - Till Date), IIT Tirupati, India
• Senior Scientist (2019 - 2021) Vaxxilon, GmbH, Germany
• Postdoctoral Fellow (2017 - 2019) Max-Planck Institute of Colloids and Interfaces, Potsdam, Germany
• Research Associate (2008-2010) Syngene Intl. Ltd., Bangalore

Latest Publications

• Sanapala, S. R.; Bruna, M. S. S.; Baek, J. Y.; Awan, S. I.; Pereira, C. L. Seeberger, P. H. Chimeric Oligosaccharide Conjugate Induces Opsonic Antibodies against Streptococcus pneumoniae Serotypes 19A and 19F. Chem. Sci., 2020,11, 7401-7407.
• Sanapala, S. R.; Kulkarni, S. S. "Expedient Route to Access Rare Deoxy Amino L-Sugar Building Blocks for the Assembly of Bacterial Glycoconjugates". J. Am. Chem. Soc. 2016, 138, 4938-4947.
• Sanapala, S. R.; Kulkarni, S. S. “From L-Rhamnose to Rare 6-Deoxy-L-Hexoses”. Org. Lett. 2016, 18, 3790-3793.
• Sanapala, S. R.; Kulkarni, S. S. Chemical Synthesis of Asparagine Linked Archaeal N-Glycan from Methanothermus fervidus. Chem. Eur. J. 2014, 20, 3578-3583.
• Sanapala, S. R.; Kulkarni, S. S. One-pot Synthesis of Bicyclic Sugar Oxazolidinones from D-Glucosamine. RSC Adv. 2015, 5, 22426-22430.
• Rai, D.; Sanapala, S. R.; Kulkarni, S. S. Serendipitous One-pot Synthesis of Chiral Dienes from Pyranosidic 2,4-Bistriflates. Carb. Res. 2021, 505, 108351.